Dr. L. Uma

Director, National Facility for Marine Cyanobacteria
Coordinator, Bioinformatics Centre
Chair, School of Marine Sciences
Professor, Department of Marine Biotechnology
E-Mail: lumaprabakar@yahoo.com
Phone: 0431 2407084

Academic Qualification
Institution
Place
Degree
Awarded
YearField of Study
School of Biological Sciences
Madurai Kamaraj University
M.Sc.,1980Microbiology
Central Leather Research Institute
(University of Madras)
Ph.D.,1988Microbiology
Research Associate
Bharathidasan University
ICAR1987-1991Cyanobacteriology


Position and Honors
(1991-1996)
5 years
Lecturer Department of Microbiology,
Bharathidasan,University, Tiruchirappalli.
(1996-2001)
5 years
Senior LecturerDepartment of Microbiology,
Bharathidasan University, Tiruchirappalli.
(2001-2005)
4 years
ReaderDepartment of Microbiology,
Bharathidasan,University, Tiruchirappalli.
2005
Sep onwards
ProfessorNational Facility for Marine Cyanobacteria,
Bharathidasan University, Tiruchirappalli.
RESEARCH AREAS

  • Cyanobacterial Biotechnology and Bioinformatics
PUBLICATIONS
  1. Karthick. L,Arul Prakasam. P, Shylaja Naciyar. M, Sangeetha. V, Prabaharan. D, Uma. L (2015) R and Shiny based application platform for cyanobacterial genome analysis Bioinformation 11(9): 422-425 (Impact factor 0.6)

  2. Arul Prakasam. P, Karthick. L, Shylaja Naciyar. M, Sangeetha. V, Siva Sudha, Kaleel Ahamed. A, Prabaharan. D, Subramanian.G, Uma. L (2015) Cyanobacterial KnowledgeBase (CKB), a compendium of cyanobacterial genomes and proteomes PLoS ONE 10(8): e0316262 (Impact factor 3.234)

  3. Thangavel Mathimani, Lakshmanan Uma, Dharmar Prabaharan. (2015) Homogeneous acid catalysed transesterification of marine microalga Chlorella sp. BDUG 91771 lipid - An efficient biodiesel yield and its characterization. Renewable Energy 81: 523 - 533 (Impact factor 3.361)

  4. Shylajanaciyar M, Dineshbabu G, Rajalakshmi R, Subramanian G, Prabaharan D, Uma L. (2015) Analysis and Elucidation of Phosphoenolpyruvate Carboxylase in Cyanobacteria. The Protein Journal 34-1: 73-81 (Impact factor 1.039)

  5. Vaithiyalingam Shanmugasundaram Uma, Gnanasekaran D, Gopalakrishnan S, Lakshmanan U and Prabaharan D (2014) Biocalcification Mediated Remediation of Calcium Rich Ossein Effluent by Filamentous Marine Cyanobacteria Journal of Bioremediation & Biodegradation 5:7.

  6. Vijayaraghavan Rashmi, Mohandass ShylajaNaciyar, Ramamoorthy Rajalakshmi, Stanley F. D'Souza, Dharmar Prabaharan, Lakshmanan Uma (2012) Siderophore mediated uranium sequestration by marine cyanobacterium Synechococcus elongatus BDU 130911. Bioresource Technology 130: 204-210 (Impact factor 4.98)


  7. Balakrishnan Priya, Lakshmanan Uma, Abdul Khaleel Ahamed, Gopalakrishnan Subramanian, Dharmar Prabaharan (2011) Ability to use the diazo dye, C.I. Acid Black 1 as a nitrogen source by the marine cyanobacterium Oscillatoria curviceps BDU92191 Bioresource Technol 102: 7218-7223 (Impact factor 4.365)

  8. Swaminathan Palanisami, Krishna Kannan,Uma Lakshmanan (2012).Tannase activity from the marine cyanobacterium Phormidium valderianum BDU 140441. Journal of Applied Phycology, Volume 24, Issue 5, pp 1093-1098 (Impact factor 2.411).

  9. Swaminathan Palanisami, Uma Lakshmanan (2011).Role of copper in poly R-478 decolorization by the marine cyanobacterium Phormidium valderianum BDU140441. World Journal of Microbiology & Biotechnology, vol. 27, no. 3, pp. 669-677 (Impact factor 1.532).

  10. Balakrishnan Priya, Reddi K Sivaprasanth, Vincent Divya Jensi, Lakshmanan Uma, Gopalakrishnan Subramanian, Dharmar Prabaharan, (2010). Characterization of manganese superoxide dismutase from a marine cyanobacterium. Leptolyngbya valderiana BDU20041. Saline Systems 6:6 (Impact factor 3.09).

  11. D.Prabaharan, D.Arun Kumar, L.Uma, G.Subramanian (2010), Dark hydrogen production in nitrogen atmosphere - an approach for sustainability by marine cyanobacterium Leptolyngbya valderiana BDU 20041. International Journal of Hydrogen Energy, 35:10725-10730 (Impact factor - 4.053).

  12. Swaminathan Palanisami, Sushanta Kumar Saha, Uma Lakshmanan (2010).Laccase and polyphenol oxidase activities of marine cyanobacteria: a study with Poly R-478 decolourization. World Journal of Microbiology & Biotechnology, Vol. 26:63-69 (Impact factor 1.532).

  13. Saha SK, Swaminathan P, Raghavan C, Uma L, Subramanian G. (2010).Ligninolytic and antioxidative enzymes of a marine cyanobacterium Oscillatoria willei BDU 130511 during Poly R-478 decolourization. Bioresour Technol., 101(9):3076-84. (Impact factor 4.39).

  14. P.Chellapandi, D.Prabaharan, L.Uma Laxmanan. (2010), Evaluation of methanogenic activity of biogas plant slurry for monitoring co-digestion of ossein factory waters and cyanobacterial biomass. Appl Biochem Biotechnol 162: 524-535 (Impact factor 1.749)

  15. Jagadeesan Premanandh, Balakrishnan Priya, Dharmar Prabaharan and Lakshmanan Uma. (2009) Genetic heterogeneity of the marine cyanobacterium Leptolyngbya valderiana (Pseudanabaenaceae) evidenced by RAPD molecular markers and 16S rDNA sequence data. Journal of Plankton Research. 31: 1119 -1129. (Impact factor 1.749)

  16. Swaminathan Palanisami, Prabaharan Dharmar, Lakshmanan Uma (2009) Fate of few pesticide- metabolizing enzymes in the marine cyanobacterium Phormidium valderianum BDU 20041 in perspective with chlopyrifos exposure Pesticide Physiology and Biochemistry, 94: 68-72 (Impact factor 1.71)

  17. L. Uma, D. Prabaharan, B. Priya and G. Subramanian (2009). Role of cyanobacterial oxidases in bioremediation- An Overview. In : Algal Biology and Biotechnology. J.I.S. Khattar, D.P. Singh  & Gurpreet Kaur (eds.). I.K. International Publishing House Pvt. Ltd., New Delhi. pp.251-261

  18. Chellapandi Pualchamy , Prabaharan Dharmar, Uma Laxmanan. (2008) A preliminary study on co-digestion of ossein industry waste for methane production. Eur Asia J BioSci 2, 13, 110-114.

  19. Dharmar Prabaharan, Balakrishnan Priya, Lakshmanan Uma and Gopalakrishnan Subramanian (2008) Cyanobacteria - a promising candidate for biotechnology. College Sadhana 1(1): 55 - 72

  20. Venugopal Rajendran, Mallayan Palaniandavar, Palanisami Swaminathan and Lakshmanan Uma (2007). Cleavage of Proteins by a mixed Ligand copper(II) - Phenolate complex: hydrophobicity of Diimine co-ligand promotes cleavage. Journal of Inorganic Chemistry 46:10446-10448 (Impact Factor - 4.32)

  21. Sushanta Kumar Saha, Raju Das, K. N.Bora, Uma. L (2007) Biodiversity of epilithic cyanobacteria from freshwater streams of Kakoijana reserve forest, Assam, India Indian journal of microbiology 47: 219 - 232

  22. Subramanian, G., Uma, L., Priya, B. and Prabaharan, D (2007) Utilization of microalgae to address pollution problems. Indian Hydrobiology 10(2): 1- 25

  23. Priya B, Premanandh J, Dhanalakshmi, Seethalakshmi, D, Prabaharan D, and Uma L. (2007) Comparative analysis of cyanobacterial SOD - a canonical form , BMC Genomics Vol :8; 458 (Impact factor 4.21)

  24. Palanisami Swaminathan Venugopal Rajendran, Mallayan Palaniandavar, and Lakshmanan Uma Chromium induced in vivo DNA changes in marine algae Oscilltoria willei BDU 130511. 2007 International Journal On Algae, 11:394-402.

  25. Uma, L., Prabaharan, D. and Subramanian G (2006) Microalgae - A potent source of biotechnological products. In: Recent advances on applied aspects of Indian Marine Algae with references to Global Scenario. Vol.II. Application and Utilization, Food, Feed, Biotechnology, Chemistry, Drugs and Bioactive substances (ed).Tewari. A. CSMCRI Publications. Pp.52-86.

  26. Premanandh J, Priya B, Teneva I, Balik D, Prabaharan D, Uma L. (2006) Molecular characterization of marine cyanobacteria from Indian subcontinent deduced from the sequence analysis of phycocyanin operon (cpcB- IGS- cpcA) and 16S-23S IPS region. J. Microbiology 6:607-16. (Impact factor 1.46)

  27. Sushantha Kumar Saha, L.Uma, G.Subramanian. (2004) An improved method for marine cyanobacterial DNA isolation. World Journal of Microbiology and Biotechnology. 21: 877-881 (Impact Factor - 1.21)

  28. Sushanta kumar saha, Lakshmanan Uma and Subramanian, G. (2003). Nitrogen stress induced changes in the marine cyanobacterium Oscillatoria willei BDU 130511. FEMS Microbiology Ecology 45:263-272. (Impact factor 3.408)

  29. Uma, L., Kalaichelvi Selvaraj, Manjula, R., Subramanian, G., Sanjay Nagarkar. (2002) biotechnological potential ofmarine cyanobacteria in waste water treatment : Disinfection of raw sewage by the marine cyanobacterium Oscillatoria willei BDU 130511. Journal of Microbiology & Biotechnology. 12: 699-701. (Impact Factor - 1.22)

  30. Sushanta Kumar Saha, Kalib, A., Uma, L., Prabaharan, D. and Subramanian, G. (2002) An inexpensive method for denatured and native multigel in a regular vertical slab gel system. Current Science, 84(1): 27-28. (Impact factor 0.78)

  31. Francisca Kalavathi, D, Uma, L. and Subramanian, G. (2001) Ossein wastes - A potential source of biofuel. Indian Journal of Microbiology. Vol. 41, pp. 319-320.

  32. Subramanian, G and Uma, L., (2001) Potential applications of cyanobacteria in environmental biotechnology. In: Photosynthetic microorganisms in environmental biotechnology. (eds) Kojima H and Lee YK, Springer, 41-49.

  33. Francisca Kalavathi D. L. Uma and Subramanian, G. (2001) Degradation and metabolization of the pigment - melanoidin in distillery effluent by the marine cyanobacterium Oscillatoria boryana BDU 92181. Enzyme and Microbial Technology 29: 246 - 251.(Impact Factor - 2.287)

  34. Subramanian, G, and Uma, L. (2000) Potential application of cyanobacteria in environmental biotechnology. Proceedings of APEC Workshop, Japan. Page 21 -36.

  35. Subramanian, G, and Uma, L. (1999) The role of cyanobacteria in Environmental Management - Bulletin de l' Institut Oceanographique - Marine Cyanobacteria Eds. Loic Charpy & A.W.D. Larkum. 19: 599-606.

  36. Rama Rao Karna, Uma, L., Subramanian, G. and Maruthi Mohan, P. (1999). Biosorption of toxic metal ions by alkali-extracted biomass of a marine cyanobacterium, Phormidium valderianum BDU 30501. World Journal of Microbiology and Biotechnology 15:729-732. (Impact Factor - 1.21)

  37. Uma, L., Palanisamy, M., Murugaian, P., Akbarsha, M.A. and Subramanian. G. (1998) Novel cyanobacterial feed for frog tadpoles. In: "Cyanobacterial Biotechnology" Proceedings of the International Symposium, Oxford and IBH Publishers, New Delhi. pp. 311-313.

  38. S Shashirekha, L Uma, Subramanian, G (1997) Phenol degradation by the marine cyanobacterium Phormidium valderianum BDU 30501. J. Industrial Microbiology & Biotechnology 19:130-133 (Impact Factor - 2.41)

  39. Malliga, P., Uma, L., and Subramanian, G. (1996). Lignolytic activity of the cyanobacterium Anabaena azollae ML2 and the value of coir waste as a carrier for BGA biofertilizer. Microbios 86:175-183.

  40. Subramanian, G. and Uma, L. Cyanobacteria in pollution control. (1996) Journal of Scientific & Industrial Research. 55: 685-692 (Impact Factor - 0.51)

  41. Uma, L., Kalaiselvi, R. and Subramanian, G. (1994) Isolation of a lignolytic bacterium for the degradation and possible utilization of coir waste. Biotechnology Letters. 16: 303-308. (Impact Factor - 1.76)

  42. Subramanian, G., Sophia Rajini, V. and L. Uma, (1992) Studies on cyanobacterial immobilization, In: Biological Nitrogen Fixation and Biogas Technology, p.7-11.

  43. Uma, L. and Subramanian, G. (1990) Effective use of cyanobacteria in effluent treatments. In: Proc. National Symposium on Cyanobacterial Nitrogen Fixation, IARI, New Delhi. pp. 437-444.

TECHNOLOGY TRANSFERRED (one of the Investigator)

  1. Cyanobacterial Phycocyanin, beta Lactamase, aqua feed Production - simple and inexpensive technology has been transferred to ABL Biotech, Chennai.

    • Aquafeed - A nutritive and nontoxic aquaculture feed using a marine cyanobacterium that can substitute expensive imported feeds has been developed and tested with fishes, prawns and frogs.

    • Blue natural colourant - A natural protein colourant, which has applications in immunodiagnostics and cosmetics.

    • Beta lactamase production - The enzyme has found applications to treat penicillin contaminated dairy products and blood before use.

  2. Novel Pharmaceuticals from marine cyanobacteria - technology transferred to ABL Biotech, Chennai.

    • Anti-viral properties from Marine Cyanobacterium for the HBV, HIV and HSV viruses tested under laboratory conditions.
DETAILS OF RESEARCH PROJECTS

Title of the Project and AgencyPresent status
 As Investigator

1. National Facility for Marine Cyanobacteria

Dept. of Biotechnology, Govt. of India funded (Rs. 272.27 lakhs)

2002 - 2012 completed

 2. Marine Cyanobacteria - a potential candidate for uranium mining

Dept. of Atomic Energy (DAE) Govt. of India funded (Rs. 21.72 lakhs)

2007 - 2012 Completed

3. CO2 sequestration of marine cyanobacteria for multiple utilization potentials

Dept. of Science and Technology, Govt. of India funded (Rs. 49.08 lakhs)
2009 - 2012 Completed

4. Bioinformatics Centre - (Sub DIC)

Dept. of Biotechnology, Govt. of India funded (Rs. 169.71 Lakhs)
2002 - 2017 Ongoing

5. Adaptive responses of psychrophilic (Arctic) and mesophilic cyanobacterial diazotrophs to temperature regimes

University Grant Commission funded (15.458 Lakhs)
2013 - 2016 Ongoing

6. Indo - UK, Sustainable bio-energy from microalgae - A systems perspective

Dept. of Biotechnology, Govt. of India funded (152.272 Lakhs)
2013 - 2016 Ongoing

7. Comprehensive analysis of Cyanobacterial Glutathione S- Transferases: New Insights and Perspectives

Dept. of Biotechnology, Govt. of India funded (49.40 Lakhs)
2013 - 2016 Ongoing

 8. Establishment of National Repository for Microalgae and Cyanobacteria

Dept. of Biotechnology, Govt. of India funded (85.37 lakhs)

2015 - 2018
Ongoing
As Co- Investigator

 1. Over Expression of Engineered SOD Enzyme in Marine Cyanobacteria for Bioremediation Purposes

Dept. of Biotechnology, Govt. of India funded (Rs. 22.57 lakhs)

2003 - 2007 Completed

 2. Marine Cyanobacteria - A Potential Target for Hydrogen Photoproduction

 Dept. of Biotechnology, Govt. of India funded (Rs. 27.03 lakhs)

2006 - 2009 Completed

 3. Repository of marine cyanobacteria for biodiesel feed stock

 Dept. of Biotechnology, Govt. of India funded (Rs. 70.38 lakhs)

2009 - 2014 Completed

 4. Molecular Diversity of Indian fresh water and marine cyanobacterial isolates from 'Hotspots' and their biotechnological potentials as bio-surfactants, flocculants

 Joint (Twinning) Project with Institute of Bioresources and Sustainable Development (IBSD), Imphal, Manipur,

Dept. of Biotechnology, Govt. of India funded (Rs. 31.75 lakhs)

2012 - 2015 Completed
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