|| Dr.D.Prabaharan - Group Leader|
|Professor- National Facility for Marine Cyanobacteria,|
Department of Marine Biotechnology, School of Marine Sciences,
Bharathidasan University, Tiruchirappalli, - 620 024, Tamil Nadu
Long-term Overseas Associate (DBT, Govt.of India) University of Washington, Seattle, USA (2000-2001)|
Ph.D in Microbial Technological Unit, Department of Botany, Bharathidasan University (1993)|
M.Phil degree in Microbial Technological Unit, Department of Botany, Bharathidasan University (1988)|
Master's Degree in Madura College, Madurai Kamaraj University (1986)|
- Cyanobacterial biofuels - Hydrogen and lipid
- Dye decolourization by ROI Species
- Cyanobacterial mass cultivation
- Whole genome sequencing and comparative genomics of cyanobacteria
- Upgradation of Cyanobacterial culture collections and molecular tagging
- Karthick. L,Arul Prakasam. P, Shylaja Naciyar. M, Sangeetha. V, Prabaharan. D, Uma. L (2015) R and Shiny based application platform for cyanobacterial genome analysis Bioinformation 11(9): 422-425 (Impact factor 0.6)
- Arul Prakasam. P, Karthick. L, Shylaja Naciyar. M, Sangeetha. V, Siva Sudha, Kaleel
Ahamed. A, Prabaharan. D, Subramanian.G, Uma. L (2015) Cyanobacterial KnowledgeBase (CKB), a compendium of cyanobacterial genomes and
proteomes PLoS ONE 10(8): e0316262 (Impact factor 3.234)
- Thangavel Mathimani, Lakshmanan Uma, Dharmar Prabaharan. (2015) Homogeneous acid catalysed transesterification of marine microalga Chlorella sp. BDUG 91771 lipid - An efficient biodiesel yield and its characterization. Renewable Energy 81: 523 - 533 (Impact factor 3.361)
- Shylajanaciyar M, Dineshbabu G, Rajalakshmi R, Subramanian G, Prabaharan D, Uma L. (2015) Analysis and Elucidation of Phosphoenolpyruvate Carboxylase in Cyanobacteria.
The Protein Journal 34-1: 73-81 (Impact factor 1.039)
- Vaithiyalingam Shanmugasundaram Uma, Gnanasekaran D, Gopalakrishnan S, Lakshmanan U and Prabaharan D (2014) Biocalcification Mediated Remediation of Calcium Rich Ossein Effluent by Filamentous Marine Cyanobacteria Journal of Bioremediation & Biodegradation 5:7.
- Vijayaraghavan Rashmi, Mohandass ShylajaNaciyar, Ramamoorthy Rajalakshmi, Stanley F. D'Souza,
Dharmar Prabaharan, Lakshmanan Uma (2012) Siderophore mediated uranium sequestration by marine cyanobacterium Synechococcus elongatus BDU 130911 Bioresource Technol 130: 204–210 (Impact factor 4.980)
- Balakrishnan Priya, Lakshmanan Uma, Abdul Khaleel Ahamed, Gopalakrishnan Subramanian, Dharmar Prabaharan (2011) Ability to use the diazo dye, C.I. Acid Black 1 as a nitrogen source by the marine cyanobacterium Oscillatoria curviceps BDU92191 Bioresource Technol 102: 7218-7223 (Impact factor 4.365)
- Balakrishnan Priya, Reddi K Sivaprasanth, Vincent Divya Jensi, Lakshmanan Uma, Gopalakrishnan Subramanian, Dharmar Prabaharan, (2010). Characterization of manganese superoxide dismutase from a marine cyanobacterium. Leptolyngbya valderiana BDU20041. Saline Systems 6:6 (Impact factor 3.09).
- D.Prabaharan, D.Arun Kumar, L.Uma, G.Subramanian (2010), Dark hydrogen production in nitrogen atmosphere - an approach for sustainability by marine cyanobacterium Leptolyngbya valderiana BDU 20041. International Journal of Hydrogen Energy, 35:10725-10730 (Impact factor - 4.053).
- P.Chellapandi, D.Prabaharan, L.Uma Laxmanan. (2010), Evaluation of methanogenic activity of biogas plant slurry for monitoring co-digestion of ossein factory waters and cyanobacterial biomass. Appl Biochem Biotechnol 162: 524-535 (Impact factor 1.749)
- Jagadeesan Premanandh, Balakrishnan Priya, Dharmar Prabaharan and Lakshmanan Uma. (2009) Genetic heterogeneity of the marine cyanobacterium Leptolyngbya valderiana (Pseudanabaenaceae) evidenced by RAPD molecular markers and 16S rDNA sequence data. Journal of Plankton Research. 31: 1119 -1129. (Impact factor 1.749)
- Swaminathan Palanisami, Prabaharan Dharmar, Lakshmanan Uma (2009) Fate of few pesticide- metabolizing enzymes in the marine cyanobacterium Phormidium valderianum BDU 20041 in perspective with chlopyrifos exposure Pesticide Physiology and Biochemistry, 94: 68-72 (Impact factor 1.71)
- L. Uma, D. Prabaharan, B. Priya and G. Subramanian (2009). Role of cyanobacterial oxidases in bioremediation- An Overview. In : Algal Biology and Biotechnology. J.I.S. Khattar, D.P. Singh & Gurpreet Kaur (eds.). I.K. International Publishing House Pvt. Ltd., New Delhi. pp.251-261
- Chellapandi Pualchamy , Prabaharan Dharmar, Uma Laxmanan. (2008) A preliminary study on co-digestion of ossein industry waste for methane production. Eur Asia J BioSci 2, 13, 110-114.
- Dharmar Prabaharan, Balakrishnan Priya, Lakshmanan Uma and Gopalakrishnan Subramanian (2008) Cyanobacteria - a promising candidate for biotechnology. College Sadhana 1(1): 55 - 72
- Subramanian, G., Uma, L., Priya, B. and Prabaharan, D (2007) Utilization of microalgae to address pollution problems. Indian Hydrobiology 10(2): 1- 25
- Priya B, Premanandh J, Dhanalakshmi, Seethalakshmi, D, Prabaharan D, and Uma L. (2007) Comparative analysis of cyanobacterial SOD - a canonical form , BMC Genomics Vol :8; 458 (Impact factor 4.21)
- Uma, L., Prabaharan, D. and Subramanian G (2006) Microalgae - A potent source of biotechnological products. In: Recent advances on applied aspects of Indian Marine Algae with references to Global Scenario. Vol.II. Application and Utilization, Food, Feed, Biotechnology, Chemistry, Drugs and Bioactive substances (ed).Tewari. A. CSMCRI Publications. Pp.52-86.
- Premanandh J, Priya B, Teneva I, Balik D, Prabaharan D, Uma L. (2006) Molecular characterization of marine cyanobacteria from Indian subcontinent deduced from the sequence analysis of phycocyanin operon (cpcB- IGS- cpcA) and 16S-23S IPS region. J. Microbiology 6:607-16. (Impact factor 1.46)
- Sushanta Kumar Saha, Kalib, A., Uma, L., Prabaharan, D. and Subramanian, G. (2002) An inexpensive method for denatured and native multigel in a regular vertical slab gel system. Current Science, 84(1): 27-28. (Impact factor 0.78)
- Prabaharan, D. and Subramanian, G. (1996). Oxygen free hydrogen production by the marine cyanobacterium Phormidium valderianum BDU 20041. Bioresource. Technol. 57:111-116. (Impact factor 4.365)
- Prabaharan, D. and Subramanian, G. (1995) Hydrogen production by marine cyanobacterium Dichothrix baueriana BDU 40481. Physiology & Molecular Biology of Plants. Vol. I(1): 45-57.
- Subramanian, G. and Prabaharan, D. (1994) Cyanobacterial hydrogen production. J. Swamy Botanical Club. 11:1-11
- Prabaharan, D., Sumathi, M. and Subramanian, G. (1994) Ability to use ampicillin as a nitrogen source by marine cyanobacterium Phormidium valderianum BDU 30501. Current Microbiology. 28:315-320. (Impact factor 1.33)
- Subramanian, G., Sundararaman, M., Thajuddin, N., Prabaharan, D. and Sekar, S. (1987) Survey of cyanobacterial flora in the southern east coast of India. In: Advances in Applied Phycology-II (Ed.) A.C. Shukla, Today and Tomorrow's Printers Publishers, New Delhi. pp.307-321.0.
|GENE SEQUENCES SUBMITTED|
- Prabaharan, D., Reddi Sivaprasanth, K., Priya, B., Sajith, V., PremAnandh, J., Uma, L., Subramanian G. Partial sequence of Manganese Superoxide dismutase gene of Leptolyngbya valderiana BDU20041, Accession number AY974247
- As a result of molecular characterization, The Co-PI along PI has submitted 60 nucleotide sequences of 16sRNA, ITS, CPC regions of order Oscillatorials to Genbank.
- Cyanobacterial plasmid has been partially sequenced as a preliminary step to vector development (Genome Accession No: AAZV00000000)
- Involved in Cyanobacterial Genome sequencing project
TECHNOLOGY TRANSFERRED (one of the Investigator)
- Cyanobacterial Phycocyanin, beta Lactamase, aqua feed Production - simple and inexpensive technology has been transferred to ABL Biotech, Chennai.
Aquafeed - A nutritive and nontoxic aquaculture feed using a marine cyanobacterium that can substitute expensive imported feeds has been developed and tested with fishes, prawns and frogs.
- Blue natural colourant - A natural protein colourant, which has applications in immunodiagnostics and cosmetics.
- Beta lactamase production - The enzyme has found applications to treat penicillin contaminated dairy products and blood before use.
Novel Pharmaceuticals from marine cyanobacteria - technology transferred to ABL Biotech, Chennai.
- Anti-viral properties from Marine Cyanobacterium for the HBV, HIV and HSV viruses tested under laboratory conditions.
- Young Scientist award to attend the IUMS Congress '96 - 8th International Congress of Bacteriology and Applied Microbiology division, 8th International congress of Mycology division, Jerusalem, Israel.
- Long term Overseas Associateship - 99 visit to Department of Medicinal Chemistry, University of Washington, Seattle, USA.
- Best poster presentation award, International Conference of Association of Microbiologists of India, Mysore. 1994.
- Best poster presentation award, - Suggestive synergistic roles of marine cyanobacterial oxidases, oxygenases/oxidants in lignin model dye decolourization. International Conference on Applied Phycology - 2006. Dept. of Botany, University of Delhi, New Delhi, Feb. 14-15, 2006.
- Arctic Expedition 2011.
- Antarctic Expedition 2013.
- Arctic Expedition 2014.
|DETAILS OF RESEARCH PROJECTS|
|Title of the Project and Agency||Present status|
1. Over Expression of Engineered SOD Enzyme in Marine Cyanobacteria for Bioremediation Purposes
Dept. of Biotechnology, Govt. of India funded (Rs. 22.57 lakhs)
|2003 - 2007
2. Marine Cyanobacteria - A Potential Target for Hydrogen Photoproduction
Dept. of Biotechnology, Govt. of India funded (Rs. 27.03 lakhs)
|2006 - 2009
3. Repository of marine cyanobacteria for biodiesel feed stock
Dept. of Biotechnology, Govt. of India funded (Rs. 70.38 lakhs)
|2009 - 2013
4. Molecular Diversity of Indian fresh water and marine cyanobacterial isolates from 'Hotspots' and their biotechnological potentials as bio-surfactants, flocculants
Joint (Twinning) Project with Institute of Bioresources and Sustainable Development (IBSD), Imphal, Manipur,
Dept. of Biotechnology, Govt. of India funded (Rs. 31.75 lakhs)
|2012 - 2015
5. Establishment of National Repository for Microalgae and Cyanobacteria
Dept. of Biotechnology, Govt. of India funded (Rs. 85.37 lakhs)
|2015 - 2018
| As Co - Investigator |
1. National Facility for Marine Cyanobacteria
Dept. of Biotechnology, Govt. of India funded (Rs. 272.27 lakhs)
|2002 - 2012
2. Marine Cyanobacteria - a potential candidate for uranium mining
Dept. of Atomic Energy (DAE) Govt. of India funded (Rs. 21.72 lakhs)
|2007 - 2012
3. CO2 sequestration of marine cyanobacteria for multiple utilization potentials
Dept. of Science and Technology, Govt. of India funded (Rs. 49.08 lakhs)
|2009 - 2012
4. Bioinformatics Centre - (Sub DIC)
Dept. of Biotechnology, Govt. of India funded (Rs. 169.71 Lakhs)
|2002 - 2017
5. Adaptive responses of psychrophilic (Arctic) and mesophilic cyanobacterial diazotrophs to temperature regimes
University Grant Commission funded (15.458 Lakhs)
|2013 - 2016
6. Indo - UK, Sustainable bio-energy from microalgae - A systems perspective
Dept. of Biotechnology, Govt. of India funded (152.272 Lakhs)
|2013 - 2016
7. Comprehensive analysis of Cyanobacterial Glutathione S- Transferases: New Insights and Perspectives
Dept. of Biotechnology, Govt. of India funded (49.40 Lakhs)
|2013 - 2016
Phone: 0431 2407084